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Tables and Figures

Tables and Figures from Perspectives in Pathology


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Perspectives in Pathology

Figures
The bone marrow aspirate and biopsy procedure.
   
(a) A 16 gauge Illinois sternal/Iliac aspiration needle has been placed into the marrow cavity. The obturator of the needle has been removed and a 10 mL syringe attached to the hub. Suction is being applied to the syringe, with successful aspiration of marrow. (b) An experienced medical technologist is preparing smears from small drops of the bone marrow aspirate placed on glass microscope slides.
   
(c) A 4", 11 gauge, Snarecoil bone marrow biopsy/aspiration needle has been inserted into the posterior iliac crest for biopsy procurement. The length of biopsy core in needle is being determined by carefully reinserting obturator. Ideally, the core length should be 2 cm or greater. (d) Touch imprints of the biopsy core are being prepared by gently touching a clean glass microscope slide to the biopsy core resting on another glass slide. Cells on the surface of the core stick to the clean slide, which is later stained by the Wright-Giemsa technique. Cytologic detail of the cells can be visualized and complements the aspirate and biopsy.

Table
Indications for Bone Marrow Procedure

Major Indication

Diseases

Disease diagnosis

Pancytopenia or unexplained anemia, leucopenia or thrombocytopenia

Acute leukemia

Chronic leukemia

Myelodysplastic syndrome

Myeloproliferative disease

Plasma cell dyscrasia

Non-Hodgkin lymphoma

Hodgkin lymphoma

Aplastic anemia

Fever of unknown origin

Small cell tumors of childhood

Mast cell disease

Disseminated granulomatous disease

Thrombotic thrombocytopenic purpura

Primary amyloidosis

Metabolic bone disease

Therapeutic follow-up

Chemotherapy/bone marrow transplantation for hematopoietic neoplasms or small cell tumors of childhood

Treatment of isolated cytopenia